chances of getting a blood clot while on xarelto

Some commonly taken medications Xarelto interacts with includes: These diseases can also interact with Xarelto: Your Injury:Bladder SlingGadolinium (MRI)Hernia MeshIVC filterNuVasive MAGECParagardStryker HipSurgical StaplerTransvaginal Mesh------AbilifyActosAduhelmBelviqCymbaltaEffexorElmironEssureGranufloDepakoteGeodonInvegaInvokanaLyricaNexiumOpioidsParaquatRisperdalRoundupTestosterone therapyTalcum PowderTaxotereXareltoZantacZofranZoloftZinbryta, State:AL AlabamaAK AlaskaAZ ArizonaAR ArkansasCA CaliforniaCO ColoradoCT ConnecticutDE DelawareFL FloridaGA GeorgiaHI HawaiiID IdahoIL IllinoisIN IndianaIA IowaKS KansasKY KentuckyLA LouisianaME MaineMD MarylandMA MassachusettsMI MichiganMN MinnesotaMS MississippiMO MissouriMT MontanaNE NebraskaNV NevadaNH New HampshireNJ New JerseyNM New MexicoNY New YorkNC North CarolinaND North DakotaOH OhioOK OklahomaOR OregonPA PennsylvaniaRI Rhode IslandSC South CarolinaSD South DakotaTN TennesseeTX TexasUT UtahVT VermontVA VirginiaWA WashingtonWV West VirginiaWI WisconsinWY WyomingOther. For this use, the usual dosage of Xarelto is 2.5 mg taken by mouth twice a day. Xarelto may make you feel tired or fatigued (lacking energy). If your child has trouble swallowing Xarelto tablets, their doctor will prescribe Xarelto liquid suspension instead. It alerts doctors and patients about drug effects that may be dangerous. MNT is the registered trade mark of Healthline Media. In addition, one review of studies found Xarelto and Eliquis to be similarly effective in treating and preventing DVT and PE. You can also see this article for details about Xareltos interactions. If you would like to report to the FDA a side effect youve had with Xarelto, you can do so through MedWatch. Xarelto is FDA-approved to treat the following types of blood clots: Xarelto is an anticoagulant (blood thinner). (Warfarin is a different type of anticoagulant thats recommended as a treatment option for A-fib in current guidelines.). If you have a spinal or epidural injection* while youre taking Xarelto, theres a risk that the injection could cause bleeding around your spine or brain. We also use third-party cookies that help us analyze and understand how you use this website. In a clinical study of people using Xarelto to treat a deep vein thrombosis (DVT), 2.9% had back pain. (In this case, the drug is used during your hospital stay and for a period of time after youve been discharged. Stopping Xarelto before the recommended amount of treatment increases your risk of having a blood clot. For example, 1.2% of people taking Xarelto had a DVT or PE, compared with 4.4% of people taking aspirin. You may also find that it takes longer than usual for you to stop bleeding. Stopping Eliquis suddenly may increase the risk of blood clots. A generic drug is an exact copy of the active drug in a brand-name medication. Eliquis Side Effects. Internal bleeding is a rare serious side effect. The current stance of the Food and Drug Administration (FDA) is to avoid using expired medications. Xarelto may cause dizziness in some people taking the drug. Risk of blood clots if you stop taking Xarelto too soon. This reduces the production of thrombin, and subsequently fibrin, in the clotting cascade. The usual dosage of Xarelto to treat deep vein thrombosis (DVT) or pulmonary embolism (PE) is as follows: Xarelto is used to reduce your risk of having another DVT or PE if: The usual dosage of Xarelto for reducing the risk of another DVT or PE is 10 mg taken once a day. These types of surgeries can damage the blood vessels around the area of your joint replacement. This form is typically prescribed for children who cannot swallow tablets. If you have kidney disease, talk with your doctor about whether youll be able to take Xarelto. To learn more about Xarelto and its cost, you can see this article. Research studies suggest that there is about one DVT for every 4,656 flights that last for four hours or more. (Clotting factors are proteins made by your liver.) Andexxa is given as an injection into your vein. serotonin-norepinephrine reuptake inhibitors (SNRIs), such as: carbamazepine (Carbatrol, Equetro, Tegretol), having a type of irregular heartbeat called. Xarelto is FDA-approved to reduce the risk of strokes and blood clots in people with atrial fibrillation (A-fib) thats not caused by a heart valve problem. Unusually heavy vaginal bleeding. In this case, the recommended dosage of Xarelto is 15 mg taken once every evening. Scientists use genetic rewiring to increase lifespan of cells, Everything you need to know about a thrombus, What to know about deep vein thrombosis (DVT), What to know about blood thinners for heart disease, Blood-thinning foods, drinks, and supplements, Treatment and home management for blood clots, 2.6 kg to 2.9 kg (about 5.7 lb to 6.4 lb), 7 kg to 7.9 kg (about 15.4 lb to 17.4 lb), 8 kg to 8.9 kg (about 17.6 lb to 19.6 lb), 9 kg to 9.9 kg (about 19.8 lb to 21.8 lb), 12 kg to 29.9 kg (about 26.4 lb to 65.9 lb), 15 mg once per day, as a tablet or suspension*, 20 mg once per day, as a tablet or suspension*, 8 kg to 9.9 kg (about 17.6 lb to 21.8 lb), 10 kg to 11.9 kg (about 22 lb to 26.2 lb), 12 kg to 19.9 kg (about 26.4 lb to 43.8 lb), 20 kg to 29.9 kg (about 44 lb to 65.9 lb), 10 mg once per day, as a tablet or suspension*, an oral tablet, which is available in four strengths: 2.5 milligrams (mg), 10 mg, 15 mg, and 20 mg, an oral liquid suspension, which is available in a strength of 1 mg per milliliter (mg/mL). If you have trouble sleeping while youre taking Xarelto, talk with your doctor or pharmacist. If a clot breaks free, it can get stuck inside a blood vessel in your lungs. If youre taking Xarelto after having a hip replacement, youll take the drug for 35 days after your surgery. For example, some people may benefit by wearing graduated compression stockings. If you have had a previous blood clot, or if a family member has a history of blood clots or an inherited clotting disorder, talk with your doctor to learn more about your individual risks. Before taking Xarelto, talk with your doctor about your health history. (This gives a total daily dose of 5 mg.). A thrombus is a blood clot that occurs inside the vascular system. Contact your healthcare provider if your AFib episode lasts 24 to 48 hours without stopping or if symptoms worsen. In comparison, 3.9% of people taking enoxaparin had blood clots. Being seated over a long period of time increases your risk of having blood clots. The actual price youll pay depends on your insurance plan, your location, and the pharmacy you use. Children who weigh less than 30 kg are prescribed the suspension. This can increase your risk of having bleeding from Xarelto. Xarelto is FDA-approved to reduce your risk of having another blood clot if youve had one in the past. You should take Xarelto according to your doctors or healthcare professionals instructions. You may wonder how often certain side effects occur with this drug, or whether certain side effects pertain to it. Usually, your doctor will recommend that you stop taking the drug at least 24 hours before your surgery. A blood clot is more likely to form during or after surgery; one reason for this is prolonged periods of inactivity due to lying on an operating table and staying in bed while recovering. Xarelto may pass into breast milk, but its not known how this may affect a child whos breastfed. The more risks you have, the greater your chances of experiencing a blood clot. Your kidneys filter creatinine out of your blood, and it exits your body through your urine. The FDA website provides several useful tips on medication disposal. If you have questions about the use of Andexxa, talk with your doctor. It can be used for up to 12 months for this purpose. Xarelto is an anticoagulant (blood thinner). And if you have heart disease or disease that affects your arteries, stopping Xarelto increases your risk of heart attack and stroke. Are IVC Filters dangerous? St. Johns wort (Hypericum perforatum) is known to interact with Xarelto. People have an increased risk of developing a blood clot when traveling long distances. Any cookies that may not be particularly necessary for the website to function and is used specifically to collect user personal data via analytics, ads, other embedded contents are termed as non-necessary cookies. Heart attack. (Your doctor will also tell you when to start taking Xarelto again after your procedure.). Using more than the recommended dosage of Xarelto can lead to serious side effects. Blood clots affect about 1-2 in 1,000 U.S. adults per year, and the risk may double or triple after a flight that's 4+ hours. Symptoms of potentially serious bleeding can vary, but they may include: If you have any symptoms of serious bleeding, call your doctor right away. Xarelto is a brand-name prescription drug. The latter drugs are anticoagulants, which includes Xarelto. These cookies do not store any personal information. So its not known how effective the drug is for reducing the risk of heart attacks and stroke in this group of people. If your child is taking Xarelto for VTE, they should take each dose with food. The effect of Xarelto in your body isnt affected by taking vitamin K. In some cases, other drugs that prevent and treat blood clots, such as warfarin (Jantoven), are affected by vitamin K. But this isnt so with Xarelto. Keep in mind that sometimes itchy skin or a rash can be a sign of an allergic reaction to the drug. For example, 3.8% of people taking Xarelto had a stroke or blood clot. enoxaparin plus warfarin in treating DVT and PE. For information about possible symptoms of severe bleeding, see the section Xarelto side effects above. For example, blood clots occurred in 9.7% of people taking Xarelto. (The dosage of aspirin for this purpose is 75 mg to 100 mg daily[EP1].). It has to be stressed that the vast majority of travellers have no problems. And after surgery, your ability to move is restricted for a while. But even if you crush 15-mg or 20-mg tablets of Xarelto and take them mixed with applesauce, youll still need to eat some food with your dose. For more information about reversing the effects of Xarelto, see the Reversal of Xarelto section below. (Enoxaparin is a fast-acting anticoagulant thats given with warfarin at the start of treatment for blood clots. Its not certain whether these cases of hair loss were definitely caused by Xarelto or not. Taking certain antifungal drugs with Xarelto can cause Xarelto to build up in your body. Blood in your urine or stool. The longer you are immobile, the greater is your risk of developing a blood clot. Xarelto and warfarin are both anticoagulant drugs. If you take Xarelto with certain drugs used to treat HIV, you may have an increased risk of bleeding from Xarelto. * Sex and gender exist on spectrums. Examples of other anticoagulant drugs include: If you need to take one of these drugs with Xarelto, call your doctor right away if you have any symptoms of serious bleeding. They can suggest ways to help improve your quality of sleep. Its used after the Fontan procedure. The recommended dosage of aspirin for this use is 75 milligrams (mg) to 100 mg taken once a day. This is because the drug makes it harder for your blood to form clots. Cardiovascular events include heart attacks or strokes caused by blood clots. In this study, Xarelto was more effective than enoxaparin followed by a placebo (no active drug) in preventing blood clots in people admitted to the hospital. Xareltos dosage in children is based on the childs body weight in kilograms (kg). If Xarelto is taken during pregnancy, it could increase the risk of bleeding in both the pregnant person and the fetus. Xarelto is an anticoagulant medication thats used to stop dangerous blood clots from forming inside your blood vessels. Xarelto is used as prophylaxis to prevent a DVT or PE following surgery done to replace your knee or hip. minor bleeding, such as bleeding gums after brushing or flossing your teeth, increased risk of blood clots if you stop taking Xarelto too soon*, risk of spinal or epidural blood clots if you have a spinal injection while youre taking Xarelto*, swelling under your skin, typically in your eyelids, lips, hands, or feet, swelling of your tongue, mouth, or throat, any bleeding thats severe, lasts a long time, or wont stop, unexpected vaginal bleeding or menstrual bleeding thats heavier than usual, blood in your urine, which may be red, pink, or brown in color, blood in your stool, which may be red or black in color, or look like tar, vomiting blood, which may be red or pink in color, or look like coffee grounds, coughing up blood that looks like coffee grounds, dizziness, which could be a sign of low blood pressure thats caused by, pain, swelling, or bleeding at any wounds, getting up and moving around from time to time, flexing your feet forward and backward to encourage blood flow in your calves. For example, recurrent DVT or PE occurred in 1.2% of people who took Xarelto. This condition increases your risk of having blood clots that can cause a heart attack or stroke. Its unlikely that it will. This could make Xarelto less effective in treating and preventing blood clots. If you and your doctor determine that Xarelto is safe and effective for you, youll likely take it long term for these purposes. It comes as: Xarelto has been found effective in several clinical studies that compared it with other commonly used anticoagulant (blood thinning) medications. Call your doctor right away if you have serious side effects. What are possible symptoms of bleeding while using Xarelto? You should always consult your doctor or another healthcare professional before taking any medication. Your doctor will usually prescribe a different anticoagulant drug to help prevent blood clots while youre not taking Xarelto. These lists contain examples of mild side effects that can occur with Xarelto, with Eliquis, or with both drugs (when taken individually). For more information on the possible side effects of Xarelto, talk with your doctor or pharmacist. Its possible to have insomnia (trouble sleeping) while youre taking Xarelto. For more information about this, see the Reversal of Xarelto section below. Created for people with ongoing healthcare needs but benefits everyone. Xarelto may affect the results of a lab test called international normalized ratio (INR). There are many blood thinners on the market designed to prevent blood clots or keep them from reoccurring. treat and prevent some kinds of blood clots in adults and certain children. Learn. Many times the blood clot will dissolve on its own. Treatment with anticoagulants may be recommended if your doctor feels you're at an increased risk of developing one of these problems. The insurance company will review the request and let you and your doctor know if your plan will cover Xarelto. With CAD, you have narrowed arteries in your heart. As a blood thinner, Xarelto can cause minor bleeding events, such as prolonged bleeding from a cut, bruise, or nosebleed. The AUC of rivaroxaban was increased by 127% in people with moderate hepatic impairment, compared to people with normal hepatic function. Overall, your chance of getting a clot when you fly is low. After 10 days of treatment, 2.7% of people taking either Xarelto or enoxaparin had a blood clot. Bleeding in b. In fact, people who took Xarelto were 74% less likely to get another DVT or PE than people who took aspirin. CDC is not responsible for Section 508 compliance (accessibility) on other federal or private website. Metabolites are cleared in the urine and feces. The risk of travel-related blood clot is higher if you have more than one risk factor. prevent DVT and PE following hip or knee replacement surgery. Because Xarelto makes it harder for your blood to form clots and can increase your risk of bleeding, your doctor may recommend that you stop taking it for a while before your colonoscopy. Xarelto can be used in children for venous thromboembolism (VTE) treatment and prevention. Having a lumbar puncture (spinal tap) also increases the risk of spinal or epidural hematoma. This novel blood clot treatment doesn't increase bleeding risk, Why young women have more adverse outcomes after a heart attack than young men, Gut microbiome appears to fluctuate throughout the day and across seasons, One-hour endoscopic procedure could eliminate the need for insulin for type 2 diabetes, New clues to slow aging? Blood clotting disorder symptoms can vary depending on where in your body you have a blood clot. These uses are described below. In addition to the uses listed above, Xarelto may be used off-label. The boxed warnings for Xarelto are described below. This test is used to monitor your bloods ability to clot while youre taking warfarin (Jantoven), which is a different type of anticoagulant drug. Even though Xarelto lowers your risk of having blood clots, its still possible to have a blood clot while youre taking the drug. For this use, Xarelto is prescribed for people with a high risk of blood clots and a low risk of bleeding. To learn more about the conditions Xarelto is used for, our cardiovascular health hub may be helpful. In pediatric patients, Cmax is reached 1.5 to 2.2 hours after oral dosing. Xarelto is an anticoagulant drug. * A-fib is a type of irregular heartbeat. If you have itching or a rash while youre taking Xarelto, call your doctor. But theres not enough information available to say whether Xarelto increases the risk of congenital abnormalities (commonly known as birth defects) or pregnancy loss. Creatinine is a waste product thats produced by your body. Xarelto is prescribed for this use in people who arent at high risk of bleeding. See the Xarelto side effects section above for more information. Serious side effects from Xarelto can occur. Theyre also sometimes called blood thinners. But you should try to be consistent each day with the time that you choose. Renal impairment can increase exposure to rivaroxaban by 44% to 64%. Xarelto comes as an oral tablet and an oral liquid suspension. It alerts doctors and patients about drug effects that may be dangerous. The usual dosage of Xarelto to reduce the risk of stroke and blood clots in people with atrial fibrillation (A-fib) is 20 mg taken once every evening. Move your legs frequently when on long trips and exercise your calf muscles to improve the flow of blood. Its possible that grapefruit may interact with Xarelto. Centers for Disease Control and Prevention. In comparison, 1.8% of people taking both enoxaparin (Lovenox) and another blood thinner drug, such as warfarin (Jantoven), had back pain. Off-label use is when a drug thats approved to treat one condition is used to treat a different condition. See , reduce the risk of certain complications from blood clots in adults with. The risk of DVT from travel is small. (Aspirin is used in some people to help prevent blood clots. Half-life increases to between 11 and 13 hours in adults ages 60 to 76 years. Conditions that increase your risk of having a blood clot include having had a blood clot in the past, recent major surgery, or cancer. Xarelto contains the direct-acting anticoagulant (DOAC) rivaroxaban. Your doctor or pharmacist can tell you more about how Plavix and Xarelto compare. If you are flying long-distance, your risk of getting a blood clot during or shortly after the flight is about three times higher. If you are on blood thinners, also known as anticoagulants, be sure to follow your doctors recommendations on medication use. * Xarelto has a boxed warning from the FDA regarding the risks of blood clots if treatment is stopped too early and of spinal or epidural blood clots if you have certain procedures done while using this drug. If you feel tired or fatigued while youre taking Xarelto, talk with your doctor. (Enoxaparin and warfarin are other anticoagulant medications.). When this happens, your platelets can start clumping together inside your blood vessels. Acetaminophen, which is the generic name for drugs like Tylenol. Blood thinners are designed to keep blood from clotting by preventing blood platelets from clumping together, which are called antiplatelet drugs, or by lengthening the time it takes blood to form a clot. Otherwise, continuing to take the drug could increase your risk of bleeding from the procedure. Once there, the clot can cause a heart attack or stroke. If youve been sitting for a long time, take a break to stretch your legs. If youre taking Xarelto to treat a deep vein thrombosis (DVT) or pulmonary embolism (PE), youll take the drug for 6 to 12 months. Use of the terms male and female in this article refers to sex assigned at birth. See the How to take Xarelto section below for details. This drug comes with several precautions. Venous thrombosis is a condition in which a blood clot (thrombus) forms in a vein. It may be hard to tell if your . Stroke. The suspension comes with oral syringes that youll use to measure each dose of Xarelto. *** These complications include, prevent blood clots and stroke in people with A-fib, prevent blood clots and stroke in people whove had a heart valve replacement, reduce the risk of further heart attacks, strokes, blood clots, and death in people whove had a heart attack in the past, purple toes syndrome (a condition where tiny particles of cholesterol block blood supply to your toes, causing your toes to be painful and look dark or purple in color), treat and prevent deep vein thrombosis (DVT) and pulmonary embolism (PE), reduce the risk of blood clots and stroke in people with atrial fibrillation (A-fib), doesnt stop after 10 minutes of applying pressure, is caused by a serious injury or trauma to your head, is coming from wounds that may need stitches, is coming from wounds that may have a foreign body (object) stuck inside, magnesium salicylate (Doans, Percogesic). It starts treating the blood clot right away, while warfarin takes a few days to have its full effect in your body.). Learn how we can help 4.9k views Reviewed >2 years ago Thank However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Cookies used to enable you to share pages and content that you find interesting on CDC.gov through third party social networking and other websites. Xarelto has also been found effective for treating and preventing blood clots in certain children. Even if you travel a long distance, the risk of developing a blood clot is generally very small. Based on clinical studies, older people using Xarelto are more likely to have problems with bleeding than younger people are. Any medical information published on this website is not intended as a substitute for informed medical advice and you should not take any action before consulting with a healthcare professional. Do not take more Xarelto than your doctor recommends. Absorption and bioavailability of rivaroxaban are dependent on dose and are as follows: In adults, Cmax is reached 2 to 4 hours after oral dosing. As with all medications, the cost of Xarelto can vary. As with most drugs, some people can have an allergic reaction after taking Xarelto. For this use, Xarelto is taken in combination with aspirin. Xarelto is used to both treat and prevent certain types of clots. Talk with your doctor if you think you may be at risk for blood clots. * For this use, children who weigh 50 kg or more can be prescribed either Xarelto tablets or Xarelto suspension. This side effect was also reported in 1.2% of people who took enoxaparin. But opting out of some of these cookies may affect your browsing experience. But be sure to talk with your doctor for specific instructions on stopping Xarelto before you have any surgeries. They help us to know which pages are the most and least popular and see how visitors move around the site. It treats DVT and PE by preventing the clots from getting larger. For example, a blood clot that travels to your brain can cause a stroke. In fact, this herb can lower the level of Xarelto in your body, which makes Xarelto less effective for you. Your level of risk depends on the duration of travel as well as whether you have any other risks for blood clots. (Antidotes reverse the effect of another drug or substance.) (Normal creatinine clearance is generally 110 to 150 mL/min in males* and 100 to 130 mL/min in females.*). It might be prescribed for use once, twice, or three times per day. Read about the causes, symptoms, and treatments here. If these clots break loose, they can travel in your bloodstream and block blood flow to your lungs. Predictable pharmacokinetics, avoidance of routine laboratory monitoring, and lesser drug interactions have made NOACs safer and more tolerable treatment option in comparison to warfarin. Xarelto is a new generation of anticoagulants known as deep thrombin inhibitors which helps prevent clots that could cause pulmonary embolisms or deep vein thrombosis. Your doctor will determine the best dosage to fit your needs. Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. Examples of other drugs that may be used to reduce the risk of stroke and blood clots in adults with atrial fibrillation (A-fib)* include: * A-fib is a type of irregular heartbeat. Your doctor will prescribe Xarelto for this purpose if they think youre at high risk of having another blood clot. If you get a nosebleed, pinch your nose just above your nostrils for about 10 minutes. Bruises usually happen when a physical trauma causes blood to leak into surrounding tissues. Some people taking Xarelto have had thrombocytopenia (low platelet level). Examples of these antidepressants include: If you need to take an antidepressant with Xarelto, talk with your doctor about whether its safe for you to use the medications together. If youre concerned about the risks of Xarelto treatment given your age, talk with your doctor. If the hematoma is under your skin or inside a muscle, it could cause a painful lump or swelling. In people ages 60 to 75 years, the drug lasts for about 55 to 65 hours after their last dose. Andexxa is an antidote to Xarelto and other anticoagulant drugs that work the same way that Xarelto does. Meanwhile, lean forward and breathe through your mouth. Blood Clots and Long Distance Travel: Advising Patients. With A-fib, youre at an increased risk of having blood clots and stroke. The table below describes the recommended dosages for this use. Rivaroxaban is approximately 92% to 95% plasma protein bound in adults. When oral anticoagulants are managed well, the risk of recurrence is approximately 2 per 100 patient-years. reduce the risk of having another DVT or PE, if youre still at risk of blood clots after initial treatment for a DVT or PE, prevent DVT and PE following hip or knee replacement surgery, prevent blood clots in adults admitted to a hospital with an acute medical illness. For this use, Xarelto is taken in combination with aspirin. It also helps keep the drug from harming the environment. This is because certain HIV drugs can increase the level of Xarelto in your body. And in some cases, Xarelto may make you feel faint. The only exception to this is if you have atrial fibrillation (A-fib)* and youre taking Xarelto once a day to reduce your risk of stroke and blood clots. However, cases of treatment failure mainly due to interindividual . Your doctor will help you to weigh the risks of getting a blood clot against the risk of bleeding with Xarelto treatment. In comparison, 18.8% of people taking enoxaparin had blood clots. In comparison, muscle spasms occurred in 0.7% of people who took enoxaparin. Xarelto and Eliquis are both brand-name drugs. One clinical study found Xarelto was as effective as warfarin (Jantoven) in preventing stroke and blood clots in people with A-fib. Necessary cookies are absolutely essential for the website to function properly. Using a combination of Xarelto and aspirin is more effective for preventing heart attack and stroke in people with CAD or PAD than using aspirin alone. If youre concerned about hair loss while youre taking Xarelto, talk with your doctor. Blood flowing slowly is more likely to make a clot. If youre not sure if youll need to get prior authorization for Xarelto, contact your insurance company. The clots location and severity will determine the treatment. These types of activities help to improve the flow of blood in your legs. This makes your blood less able to form clots. Xarelto comes as an oral tablet and an oral liquid suspension. Throwing up blood. These liver issues included: If you have questions about how Xarelto may affect your liver, talk with your doctor. If youre taking Xarelto because you have heart disease or disease in your arteries, stopping the drug increases your risk of having a stroke or heart attack. In animal studies, fetal harm was seen when the drug was given to pregnant animals. If you plan on traveling soon, talk with your doctor to learn more about what you can do to protect your health. But in general, you should avoid any medications that contain the drugs listed above. For example, if you get a cut, apply pressure to the area with a clean cloth for about 10 minutes. Both of these issues increase your risk of having a blood clot. Because of this risk, you should not take the following pain medications while youre using Xarelto: Also, certain cold and flu medications contain pain relievers. (However, you may notice side effects from Xarelto during treatment.). In fact, liver-related side effects werent reported in people who took Xarelto during clinical studies. However, always follow the instructions given by your doctor. Xarelto is an anticoagulant (blood thinner). If youre interested in finding an alternative to Xarelto, talk with your doctor. These lists dont include all possible side effects. Its important to do this before you start taking any new medication. If youre planning to have a colonoscopy, talk with your doctor about if and when you should stop taking Xarelto.

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chances of getting a blood clot while on xarelto